- 'Hodges's book succeeds in giving the reader a faithful picture of the dementia puzzle.' -The Lancet Neurology
- 'This is a book that I expect to use regularly and profitably. I would recommend it to anyone with an interest in dementia and to those of us who work in memory clinics and continue to be challenged by our early-onset dementia cases.' -British Journal of Psychiatry
- 'This book contains a wealth of useful information, much of it presented in easily accessible format. Such is the breadth of coverage that it may be recommended to anyone involved in the diagnosis and management of patients with dementia, not only those with early-onset.' -Advances in Clinical Neuroscience and Rehabilitation
Although uncommon in comparison to dementia in the elderly, early-onset dementia presents a huge problem for patients, their carers and physicians. This is the first comprehensive and international book on the subject, encompassing the clinical and neuropsychological features as well as the relevant advances in the neurosciences and patient management. After an introductory chapter on epidemiology, the book deals with assessment and evaluation, covers disorders mimicking dementia and describes the relevant advances in imaging, molecular pathology, neurochemistry and neuropathology. The focus then shifts to the main causes of dementia including Alzheimer's disease, frontotemporal dementia, dementia with Lewy bodies, vascular dementia, Huntington's disease, prion encephalopathies and inflammatory disorders. The final section of the book deals with treatment issues including drug interventions and opportunities for non- pharmacological management. John Hodges is an acknowledged expert in this field and has assembled a team of leading academics and clinicians from around the world as contributors.
Preface
1. Epidemiology of Pre-Senile Dementia, Harvey
2. The Clinical Approach to Assessing Patients with Early Onset Dementia, Nestor & Hodges
3. Neuropsychological Assessment of Early Onset Dementia, Salmon & Hodges
4. Neuropsychiatric Assessment, Cummings & Chung
5. Psychiatric Disorders Mimicking Dementia, Berrios & Markova
6. Structural Imaging, Stevens & Fox
7. Neuroradiological Investigation: Functional Neuroimaging: SPECT/PET, Alexander & Pietrini
8. Molecular Pathology of Early Onset Dementia, McLean, Beyreuther & Masters
9. Neurochemical Pathology in Degenerative Dementias, Perry, Goodchild & Piggott
10. Neuropathology, Lantos & Cairns
11. Familial and Sporadic Alzheimer's Disease, Kennedy, Rossor & Hodges
12. Frontotemporal Dementia (Pick's Disease), Hodges & Miller
13. Dementia with Lewy Bodies, Salmon, Galasko & Hansen
14. Vascular Dementias, Hodges & Graham
15. Huntington's Disease, Paulsen & Robinson
16. Transmissible Spongiform Encephalopathies, Brown
17. Inflammatory and Infective Disorders, Wilson & Scolding
18. Dementia in Young Adults, Panegyres
19. Drug Interventions in Dementia, Rahman, Sahakian & Gregory
20. Practical Issues in the Management of Early Onset Dementia, Gregory & Lough
John Hodges