Cells Tissues & Disease 2ed
Principles of General Pathology
Guido Majno, Isabelle Joris, Guido Majno and Isabelle Joris
This book provides an up-to-date and thorough introduction to general pathology. Disease processes are explained in the light of malfunctions at the cellular level, offering a rich understanding of the clinical correlates of all aspects of fundamental cellular physiology and basic biomedicine. The book has been fully revised and updated for this Second Edition, to present a current but deep understanding of disease states at the cell and tissue levels. It includes major sections on cellular pathology, inflammation, immunopathology, vascular disturbance, and tumour biology.
Introduction
Part I: Cellular Pathology
1. The long road to the elementary patient
2. Cellular adaptations
3. Symptoms of cellular disease: Intracellular accumulations
4. Pathology of the organelles
5. Cell injury and cell death
6. Pathologic calcification
7. Extracellular pathology
Part II: Inflammation
8. Introduction to inflammation
9. Inflammation: The actors and their language
10. The four cardinal signs of inflammation
11. Leukocytes called to action: Steps to Phagocytosis
12. The inflammatory exudate
13. Chronic inflammation
14. Wound healing
15. General effects of local injury and inflammation
16. Variations and aberrations of the inflammatory response
Part III: Immunopathology
17. Hypersensitivity reactions
18. Pathology of transplantation
19. Autoimmune disease
20. Immunosuppression
21. Disturbances of fluid exchange
22. Hemostasis and thrombosis
23. Obstacles to blood flow
24. Ischemia and shock
Part V: Tumors
25. Tumors: Names and personalities
26. Anatomy and biology of tumors
27. Tumor aggression
28. The causes of tumors
29. Genes and tumors
30. Antitumor defenses
31. The reversability of tumors
32. Epidemiology of cancer
33. What is a tumor?
34. Tumors as a clinical problem
Guido Majno and Isabelle Joris
"The authors have collaborated closely over many decades. As a result...this [textbook] is cohesively and tighly written with uniformity of style and presentation. ...and the delightful, flowing language comes as a breath of fresh air. It is highly recommended for any beginning or intermediate course in biomedical sciences and pathology." --JAMA