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New Oxford Textbook of Psychiatry

Second Edition

Michael Gelder, Nancy Andreasen, Juan Lopez-Ibor, John Geddes


The New Oxford Textbook of Psychiatry is one of the leading reference works in this field. Bringing together over 200 chapters from the leading figures in the discipline, it presents a comprehensive account of clinical psychiatry, with reference to its scientific basis and to the patient's perspective throughout.

In the 8 years since publication of the first edition, many new and exciting developments have occurred in the biological sciences, which are having a major impact on how we study and practise psychiatry. In addition, psychiatry has fostered closer ties with philosophy, and these are leading to healthy discussions about how we should diagnose and treat mental illness. This new edition recognises these and other developments. Throughout, accounts of clinical practice are linked to the underlying science, and to the evidence for the efficacy of treatments. Physical and psychological treatments, including psychodynamic approaches, are covered in depth. The history of psychiatry, ethics, public health aspects, and public attitudes to psychiatry and to patients are all given due attention.

The New Oxford Textbook of Psychiatry will continue to serve the profession as an authoritative and comprehensive reference.

Part 1 - The Subject Matter of and Approach to Psychiatry
1.1: Kay Redfield Jamison, & Adam Kaplin: The patient's perspective
1.2: Graham Thornicroft, Elaine Brohan & Aliya Kassam: Public attitudes and the challenge of stigma
1.3.1: Benedetto Saraceno: Mental disorders as a worldwide public health issue
1.3.2: Julian Leff: Transcultural psychiatry
1.4: Pierre Pichot: The history of psychiatry as a medical specialty
1.5.1: Sidney Bloch & Stephen Green: Psychiatric ethics
1.5.2: K W M Fulford: Values and values-based practice in clinical psychiatry
1.6: Juan Lopez-Ibor & Costas Stefanides: The psychiatrist as manager
1.7: Andrew Sims: Descriptive phenomenology
1.8.1: John E Cooper & Margaret Oates: The principles and clinical assessment in general psychiatry
1.8.2: Robert Cloninger: The assessment of personality
1.8.3.1: Graham E Powell: Cognitive assessment
1.8.3.2: John N Hall: Questionnaire, rating and behavioural methods of assessment
1.9: Michael B First & Harold A Pincus: Diagnosis and classification
1.10: John Geddes: From science to practice
Part 2 - The Scientific Basis of Psychiatric Aetiology
2.1: Martin Davies: Brain and Mind
2.2: Graham Dunn: Statistics and the design of experiments and surveys
2.3.1: R C A Pearson: Neuroanatomy
2.3.2: Karl Zilles: Neurodevelopment
2.3.3: Charles B Nemeroff & Gretchen N Neigh: Neuroendocrinology
2.3.4: Trevor Sharp: Neurotransmitters and signalling
2.3.5: Peter Falkai & Bernhard Bogerts: Neuropathology
2.3.6: P M Grasby: Functional positron emission tomography in psychiatry
2.3.7: J Suckling & E T Bullmore: Structural magnetic resonance imaging
2.3.8: E T Bullmore & J Suckling: Functional magnetic resonance imaging
2.3.9: John G R Jeffreys: Neuronal networks, epilepsy and other brain dysfunctions
2.3.10: Robert Dantzer & Keith W Kelley: Psychoneuroimmunology
2.4.1: Anita Thapar & Peter McGuffin: Quantitative genetics
2.4.2: Jonathan Flint: Molecular genetics
2.5.1.1: William Yule & Matt Woolgar: Developmental psychology through infancy, childhood and adolescence
2.5.2: Masud Husain & Elizabeth Coulthard: Psychology of attention
2.5.3: Andreas Meyer-Lindenberg & Terry Goldberg: Psychology and biology of memory
2.5.4: Ray Dolan: The anatomy of human emotion
2.5.5: Luke Clark, Barbara Sahakian & Trevor Robbins: The neuropsychological basis of neuropsychiatry
2.6.1: George W Brown: Medical sociology and issues of aetiology
2.6.2: Arthur Kleinman: Social and cultural anthropology: salience for psychiatry
2.7: Scott Henderson: The contribution of epidemiology to psychiatric aetiology
Part 3 - Psychodynamic Contributions to Psychiatry
3.1: Otto Kernberg: Psychoanalysis: Freud's theories and their contemporary development
3.2: Jeremy Holmes: Object relations, attachment theory, self-psychology, and interpersonal psychoanalysis
3.3: Glen O Gabbard: Current psychodynamic approaches to psychiatry
Part 4 - Clinical Syndromes of Adult Psychiatry
4.1.1: Paula Trzepacz & David Meagher: Delirium
4.1.2: Simon Lovestone: Dementia: Alzheimer's disease
4.1.3: Lars Gustafson & Arne Brun: Fronto-temporal dementias
4.1.4: John Collinge: Prion disease
4.1.5: Ian G McKeith: Dementia with Lewy bodies
4.1.6: Richard Mindham & Tom Hughes: Dementia in Parkinson's disease
4.1.7: Susan Folstein & Russell Margolis: Dementia due to Huntington's disease
4.1.8: Timo Erkinjuntti: Vascular dementia
4.1.9: Mario Maj: Dementia due to HIV disease
4.1.10: Simon Fleminger: The neuropsychiatry of head injury
4.1.11: Jane Marshall: Alcohol-related dementia
4.1.12: Michael D Kopelman: Amnesic syndromes
4.1.13: Simon Fleminger & John Taylor: The management of dementia
4.1.14: Jonathan Evans: The remediation of memory disorders
4.2.1: David J Nutt & Fergus D Law: Pharmacological and psychological aspects of drug abuse
4.2.2.1: Juan C Negrete & Kathryn Gill: Aetiology of alcohol problems
4.2.2.2: Jane Marshall: Alcohol dependence and alcohol problems
4.2.2.3: Karl F Mann & Falk Keifer: Alcohol and psychiatric and physical disorders
4.2.2.4: Jonathan Chick: Treatment of alcohol dependence
4.2.2.5: D Colin Drummond: Services for alcohol use disorders
4.2.2.6: Robin Room: Prevention of alcohol-related problems
4.2.3.1: Soraya Mayet, Adam R Winstock & John Strang: Opiates: heroin, methadone, and buprenorphine
4.2.3.2: Nicholas Seivewright & Robert Fung: Disorders relating to the use of amphetamines and cocaine
4.2.3.3: Henry David Abraham: Disorders relating to the use of phencyclidine and hallucinogens
4.2.3.4: Sarah Welch & Michael Farrell: Misuse of benzodiazepines
4.2.3.5: Adam R Winstock & Fabrizio Schiffano: Disorders relating to the use of ecstasy, other 'party drugs' and khat
4.2.3.6: Richard Ives: Disorders relating to the use of volatile substances
4.2.3.7: Wayne Hall: The mental health effects of cannabis use
4.2.3.8: Maria Ines Lopez-Ibor: Nicotine dependence and treatment
4.2.4: John Marsden, Colin Bradbury & John Strang: Assessing need and organizing services for drug misusers
4.3.1: Nancy C Andreasen: Schizophrenia: a conceptual history
4.3.2.1: Peter F Liddle: Descriptive clinical features of schizophrenia
4.3.2.2: Philip Harvey: The clinical neuropsychology of schizophrenia
4.3.3: Anthony S David: Diagnosis, classification and differential diagnosis of schizophrenia
4.3.4: Assen Jablensky: Epidemiology of schizophrenia
4.3.5.1: Robin M Murray & David Castle: Genetic and environmental risk factors for schizophrenia
4.3.5.2: Paul J Harrison: The neurobiology of schizophrenia
4.3.6: Assen Jablensky: Course and outcome of schizophrenia and their prediction
4.3.7: David Cunningham Owens & Eve C Johnstone: Treatment and management of schizophrenia
4.3.8: Ming T Tsuang, William S Stone & Stephen V Faraone: Schizoaffective and schizotypal disorders
4.3.9: Jean Garrabe & Francois-Regis Cousin: Acute and transient psychotic disorders
4.4: Alistair Munro: Persistent delusional symptoms and disorders
4.5.1: John Geddes: Introduction to mood disorders
4.5.2: Per Bech: Clinical features of mood disorders and mania
4.5.3: Gordon Parker: Diagnosis, classification and differential diagnosis of mood disorders
4.5.4: Peter R Joyce: Epidemiology of mood disorders
4.5.5.1: Pierre Oswald, D Souery & J Mendlewicz: Genetic aetiology of mood disorders
4.5.5.2: Guy Goodwin: Neurobiological aetiology of mood disorders
4.5.6: Jules Angst: Course and prognosis of mood disorders
4.5.7: Eugene S Paykel & Jan Scott: Treatment of mood disorders
4.5.8: Hagop S Akiskal: Dysthymia, cyclothymia and hyperthymia
4.6.1: Anke Ehlers & Richard Bryant: Acute stress reactions
4.6.2: Anke Ehlers: Post-traumatic stress disorders
4.6.3: Chris R Brewin: Recovered memories and false memories
4.6.4: James J. Strain, Kimberly Klipstein & Jeffrey Newcorn: Adjustment disorders
4.6.5: Beverley Raphael: Bereavement
4.7.1: Stella Bitran, David H. Barlow & David A. Spiegel: Generalized anxiety disorders
4.7.2: Michelle A. Blackmore, Brigette A Erwin, Richard G Heimberg, Leanne Magee & David M Fresco: Social anxiety disorder and specific phobias
4.7.3: James C Ballenger: Panic disorders and agoraphobia
4.8: Joseph Zohar, Leah Fostick & Elizabeth Juven-Wetzler: Obsessive compulsive disorder
4.9: Nick Medford, Mauricio Sierra-Siegert & Anthony David: Depersonalization disorder
4.10.1: Gerald Russell: Anorexia nervosa
4.10.2: Christopher G Fairburn, Zafra Cooper & Rebecca Murphy: Bulimia nervosa
4.11.1: Roy J Levin: Normal sexual function
4.11.2: Cynthia Graham & John Bancroft: The sexual dysfunctions
4.11.3: J Paul Federoff: The paraphilias
4.11.4: Richard Green: Gender identity disorder in adults
4.12.1: Juan Lopez-Ibor: Personality disorders: an introductory perspective
4.12.2: James Reich & Giovanni de Girolamo: Classification and assessment of personality disorders
4.12.3: Jose Luis Carrasco & Dusica Lecic-Tosevski: Specific types of personality disorder
4.12.4: Francesca Guzzetta & Giovanni di Girolamo: Epidemiology of personality disorders
4.12.5: Adolf Tobeña: Neuropsychological templates for abnormal personalities: from genes to biodevelopmental pathways
4.12.6: Anthony Bateman & Peter Fonagy: Psychotherapy for personality disorders
4.12.7: Giles Newton-Howes & Kate Davidson: Management of personality disorder
4.13.1: Susan L McElroy & Paul E Keck, Jr: Impulse control disorders
4.13.2: Emmanuel Moran: Special psychiatric problems relating to gambling
4.14.1: Gregory Stores: Introduction to sleep-wake disorders
4.14.2: Colin A Espie & Delwyn J. Bartlett: Insomnias
4.14.3: Michel Billiard: Excessive sleepiness
4.14.4: Carlos H Schenk & Mark W Mahowald: Parasomnias
4.15.1: Jouko K Lonnqvist: Epidemiology and causes of suicide
4.15.2: Ella Arensman & Ad J F M Kerkhof: Deliberate self-harm: epidemiology and risk factors
4.15.3: J John Mann & Dianne Currier: Biological aspects of suicidal behaviour
4.15.4: Keith Hawton & Tatiana Taylor: Treatment of suicide attempters and prevention of suicide and attempted suicide
4.16: Wen-Shing Tseng: Culture-related specific psychiatric syndromes
Part 5 - Psychiatry and Medicine
5.1: Michael Sharpe & Jane Walker: Mind-body dualism, psychiatry and medicine
5.2.1: Richard Mayou: Somatoform disorders and functional symptoms
5.2.2: Gregory Simon: Epidemiology of somatoform disorders and other causes of unexplained medical symptoms
5.2.3: Per Fink: Somatization disorder and related disorders
5.2.4: Christopher Bass: Conversion and dissociation disorders
5.2.5: Russell Noyes Jr: Hypochondriasis
5.2.6: Sidney Benjamin & Stella Morris: Pain disorder
5.2.7: Michael Sharpe & Simon Wessely: Chronic fatigue syndrome
5.2.8: Katherine A Phillips: Body dysmorphic disorder
5.2.9: Christopher Bass & David Gill: Factitious disorder and malingering
5.2.10: Felice Lieh Mak: Neurasthenia
5.3.1: Allan House: Adjustments to illness and handicap
5.3.2: Maria A Ron: Psychiatric aspects of neurological disease
5.3.3: Brian Toone: Epilepsy
5.3.4: James R Rundell: Medical conditions associated with psychiatric disorder
5.3.5: Jose Luis Ayuso-Mateos: Psychiatric aspects of infections
5.3.6: S A Hales, Susan E Abbey & Gary M Rodin: Psychiatric aspects of surgery (including transplantation)
5.3.7: Jimmie C Holland & Jessica Stiles: Psychiatric aspects of cancer
5.3.8: Ulrik Frederik Malt: Psychiatric aspects of accidents, burns and other trauma
5.4: Ian Brockington: Obstetric and gynaecological conditions associated with psychiatric disorder
5.5: Pier Maria Furlan & Luca Ostacoli: Management of psychiatric disorders in medically ill patients
5.6: John Weinman & Keith J Petrie: Health psychology
5.7: Frits J. Huyse, Roger Kathol, Wolfgang Söllner & Lawson Wulsin: The organization of psychiatric services for general hospital departments
Part 6 - Treatment Methods in Psychiatry
6.1.1: Clive Adams: The evaluation of physical treatments
6.1.2: Paul Crits-Christoph: The evaluation of psychological treatment
6.2.1: Jeffrey K Aronson: General principles of drug therapy in psychiatry
6.2.2: Malcolm Lader: Anxiolytics and hypnotics
6.2.3: Zubin Bhagwagar & George R Heninger: Antidepressants
6.2.4: Robert Post: Lithium and related mood stabilizers
6.2.5: Herbert Y Meltzer & William V Bobo: Antipsychotic and anticholinergic drugs
6.2.6: Brian P Brennan & Harrison G Pope Jr: Antiepileptic drugs
6.2.7: Leslie Iversen: Drugs for cognitive disorders
6.2.8: Fergus D Law & David J Nutt: Drugs used in the treatment of addictions
6.2.9: Ursula Werneke: Complementary medicines
6.2.10.1: Max Fink: Electroconvulsive therapy
6.2.10.2: Philip J Cowen: Phototherapy
6.2.10.3: Declan McLoughlin & Andrew Mogg: Transcranial magnetic stimulation
6.2.11: Keith Matthews & David Christmas: Neurosurgery for psychiatric disorders
6.3.1: Diana Sanders: Counselling
6.3.2.1: David M Clark: Cognitive-behaviour therapy for anxiety disorders
6.3.2.2: Zafra Cooper, Rebecca Murphy & Christopher G Fairburn: Cognitive-behaviour therapy for eating disorders
6.3.2.3: Melanie J V Fennell: Cognitive-behaviour therapy for depressive disorders
6.3.2.4: Max Birchwood & Elizabeth Spencer: Cognitive-behaviour therapy for schizophrenia
6.3.3: Carlos Blanco, John Markowitz & Myrna M Weissman: Interpersonal psychotherapy for depression and other disorders
6.3.4: Amy M Ursano & Robert J Ursano: Brief individual psychodynamic psychotherapy
6.3.5: Peter Fonagy: Psychoanalysis and other long-term dynamic psychotherapies
6.3.6: John Schlapobersky & Malcolm Pines: Group methods in adult psychiatry
6.3.7: Michael Crowe: Psychotherapy with couples
6.3.8: Sidney Bloch & Edwin Harari: Family therapy
6.3.9: David Kennard & Rex Haigh: Therapeutic communities
6.4.1: Wulf Roessler: Rehabilitation techniques
6.4.2: Kevin Gournay: Psychiatric nursing techniques
6.4.3: Shulamit Ramon: Social work approaches to mental health work: international trends
6.4.4: Diane Waller: Art therapy
6.5: Wen-Shing Tseng: Indigenous folk healing practices
Part 7 - Social Psychiatry and Service Provision
7.1: Matt Muijen & Andrew McCulloch: Public policy and mental health
7.2: Michael Slade, Michele Tansella & Graham Thornicroft: Service needs of individuals and populations
7.3: Jim van Os & Kwame Mackenzie: Cultural differences care pathways, service use, and outcome
7.4: Jose Manuel Bertolote: Primary prevention of mental disorders
7.5: Tom Burns: Planning and providing mental health services for a community
7.6: Michele Tansella & Graham Thornicroft: Evaluation of mental health services
7.7: Martin Knapp & Daniel Chisholm: Economic analysis of mental health services
7.8: David Goldberg, André Tylee & Paul Walter: Psychiatry in primary care
7.9: Vanessa Pinfold & Mary Teasdale: The role of the voluntary sector
7.10.1: Richard F Mollica, Melissa A Culhane & Daniel H Hovelson: The special psychiatric problems of refugees
7.10.2: Tom K J Craig: Mental health services for homeless mentally ill people
7.10.3: Tom K J Craig & Dinesh Bhugra: Mental health services for ethnic minorities
Part 8 - The Psychiatry of Old Age
8.1: Alan Bittles: The biology of ageing
8.2: Sarah Harper & Sue Marcus: The sociology of normal ageing
8.3: Laura Fratiglioni & Scott Henderson: The ageing population and the epidemiology of mental disorders among the elderly
8.4: Robin Jacoby: Assessment of mental disorders in older patients
8.5.1: James Lindesay: Delirium in the elderly
8.5.1.1: Claudia Jacova & Howard Feldman: Mild cognitive impairment
8.5.2: Henry O'Connell & Brian Lawlor: Substance use disorders in elderly people
8.5.3: Barton W Palmer, Gauri N Savla & Thomas Meeks: Schizophrenia and paranoid disorders of late life
8.5.4: Robert Baldwin: Mood disorders in the elderly
8.5.5: James Lindesay: Stress-related, anxiety, and obsessional disorders in elderly people
8.5.6: Suzanne Holroyd: Personality disorders in the elderly
8.5.7: Robin Jacoby: Suicide and deliberate self-harm in elderly people
8.5.8: John Kellett & Catherine Oppenheimer: Sex in old age
8.6: Catherine Oppenheimer: Special features of psychiatric treatment for the elderly
8.7: Pamela Melding: The planning and organization of services for older adults
Part 9 - Child and Adolescent Psychiatry
9.1.1: Stephen Scott: Developmental psychopathology and classification in childhood and adolescence
9.1.2: E Jane Costello & Adrian Angold: Epidemiology of psychiatric disorders in childhood and adolescence
9.1.3: Jeff Bostic & Andres Martin: Assessment in child and adolescent psychiatry
9.1.4: Rhoshel Lenroot: Prevention of mental disorder in childhood and other public health issues
9.2.1: James C Harris: Developmental neuropsychiatric disorders
9.2.2: Helmut Remschmidt & Gerd Schulte-Korne: Specific developmental disorders in childhood & adolescence
9.2.3: Fred R Volkmar & Ami Klin: Autism and the pervasive developmental disorders
9.2.4: Eric Taylor: Attention deficit and hyperkinetic disorders in childhood and adolescence
9.2.5: Stephen Scott: Conduct disorders in childhood and adolescence
9.2.6: Daniel Pine: Anxiety disorders in childhood and adolescence
9.2.7: David Brent & Boris Birmaher: Paediatric mood disorders
9.2.8: Martine Flament & Philippe Robaey: Obsessive-compulsive disorder and tics in children and adolescents
9.2.9: Gregory Stores: Sleep disorders in children and adolescents
9.2.10: David Shaffer, Cynthia R Pfeffer & Jennifer Gutstein: Suicide and attempted suicide in children and adolescents
9.2.11: Judith Clegg: Children's speech and language difficulties
9.2.12: Richard Green: Gender identity disorder in children and adolescents
9.3.1: Barbara Maughan: The influence of family, school and the environment
9.3.2: David Trickey & Dora Black: Child trauma
9.3.3: David P H Jones: Child abuse and neglect
9.3.4: Julia Gledhill & Elena Garalda: The relationship between physical and mental health in children and adolescents
9.3.5: June Thoburn: The effects on child and adult mental health of adoption and foster care
9.3.6: Paul Ramchandani, Lynne Murray & Alan Stein: Effects of parental psychiatric and physical illness on child development
9.3.7: Dora Black & David Trickey: The effects of bereavement in childhood
9.4.1: John B Pearce & Anne E Thompson: The child as witness
9.5.1: John B Pearce: Counselling and psychotherapy for children
9.5.2: Peter Fonagy & Mary Target: Child psychoanalysis
9.5.3: Philip Graham: Cognitive behaviour therapies for children and adolescents
9.5.4: Philip A Fisher & Elizabeth A Stormshak: Interventions for parents and families: a developmental psychopathology perspective
9.5.5: Paramala Santosh: Medication for children and adolescents
9.5.6: Leslie Hicks & Ian Sinclair: Residential care for social reasons
9.5.7: Miranda Wolpert: Organization of services for children and adolescents
9.5.8: Gillian Forrest: The treatment of child and adolescent psychiatric emergencies
9.5.9: Simon Gowers & Sian Thomas: The child psychiatrist as consultant to schools and colleges
Part 10 - Intellectual Disability
10.1: Anthony J Holland: Classification, diagnosis, psychiatric assessment and needs assessment
10.2: Sally-Ann Cooper & Elita Smiley: Epidemiology of psychiatry of learning disability
10.3: Markus Kaski: Aetiology of intellectual disability: general issues and prevention
10.4: David Clarke & Shoumitro Deb: Syndromes causing intellectual disability
10.5.1: Bruce J Tonge: Psychiatric and behaviour disorders among children and adolescents with intellectual disability
10.5.2: A Dosen: Psychiatric and behaviour disorders among adult persons with intellectual disability
10.5.3: Matti Iivanainen: Epilepsy and epilepsy-related behaviour disorders among people with intellectual disability
10.6: T P Berney: Methods of treatment
10.7: Jane Hubert & Sheila Hollins: Special needs of adolescents and elderly people with intellectual disability
10.8: Ann Gath & Jane McCarthy: Families with a member with intellectual disability and their needs
10.9: Nick Bouras & Geraldine Holt: The planning and provision of psychiatric services for adults with intellectual disability
Part 11 - Forensic Psychiatry
11.1: Michael Gunn & Kay Wheat: General principles of law relating to people with mental disorder
11.2: David P Farrington: Psychosocial causes of offending
11.3.1: Lindsay Thomson & Rajan Darjee: Associations between psychiatric disorder and offending
11.3.2: Andrew Johns: Offending, substance misuse and mental disorder
11.3.3: Norbert Nedopil: Cognitive disorders, epilepsy, ADHD and offending
11.4.1: James Ogloff: Mental disorders among offenders in correctional settings
11.4.2: Jennifer Shaw & Nicola Swinson: Homicide offenders including mass murder and infanticide
11.4.3: David V James: Fraud, deception and thieves
11.4.4: Susan Bailey: Juvenile delinquency and serious antisocial behaviour
11.5.1: Stephen Hucker: Child molesters and other sexual offenders
11.5.2: Herschel Prins: Arson (fire-raising)
11.5.3: Paul E Mullen: Stalking
11.5.4: Paul E Mullen: Querulous behaviour: vexatious litigation, abnormally persistent complaining and petitioning
11.5.5: Gillian C Mezey: Domestic violence
11.6: Gillian C Mezey & Ian Robbins: The impact of victimization
11.7: Paul E Mullen & James Ogloff: Assessing and managing the risks of violence towards others
11.8: John O'Grady: The expert witness in the criminal court: assessment, reports and testimony
11.9: James Ogloff: Managing offenders with psychiatric disorders in general psychiatric services
11.10: Pamela J Taylor & Emma Dunn: Management of offenders with mental disorder in specialist forensic mental health services

Edited by Michael Gelder , Emeritus Professor of Psychiatry, Warneford Hospital, University of Oxford, Oxford, UK

Nancy Andreasen , Director, Mental Health Clinical Research Center, University of Iowa Hospitals and Clinics, Iowa City, USA

Juan Lopez-Ibor , Professor of Psychiatry, Complutense University, Madrid, Spain

John Geddes , Professor of Epidemiological Psychiatry, Warneford Hospital, University of Oxford, Oxford, UK

`A fantastic textbook: the best I have found in my professional career...It's informative, beautiful, easy to use and enjoyable to read.' BMA Medical Book Competition

`This is a terific second edition of an epic textbook of psychiatry. It is a pleasure to read and use as an authoritative reference source. It represents an outstanding effort.' Doody's Notes