Developmental Biology, twelfth edition, engages students and empowers instructors to effectively teach both the stable principles and the newest front-page research of this vast, complex, and multi-disciplinary field.

This much loved, well-illustrated, and remarkably well written textbook invigorates the classical insights of embryology with cutting edge material, and makes the most complex topics understandable to a new generation of students.

Designed with the undergraduate student in mind, this new, streamlined edition now contains studies of plant development, expanded coverage of regeneration, over a hundred new and revised illustrations, and deeply integrated active learning resources that build on the text's enthusiasm and accuracy. This is a text designed to make students become excited about how animals and plants develop their complex bodies from simple origins.

NEW TO THIS EDITION

• A focused and streamlined presentation of essential content highlights the important principles of each section
• New Further Development feature makes for easy distinction between foundational and advanced coverage in each chapter both in the text and online
• New content on plant development is now included throughout the book to help students appreciate common developmental principles across organisms
• A new introductory chapter encompasses the big picture and introduces common themes that students will encounter throughout the book
• An upgraded and comprehensive chapter on regeneration reflects the excitement of new discoveries in this expanding area of developmental biology
• Thoroughly updated chapters include important new studies on single cell transcriptomes, stem cell niches, cell communication during morphogenesis, fertilization, CRISPR technology, and the effects of global climate
• An upgraded illustration program includes more than 125 new and revised figures

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PART I. PATTERNS AND PROCESSES OF BECOMING: A FRAMEWORK FOR UNDERSTANDING ANIMAL DEVELOPMENT

1. Making New Bodies: Mechanisms of Developmental Organization

2. Specifying Identity: Mechanisms of Developmental Patterning

3. Differential Gene Expression: Mechanisms of Cell Differentiation

4. Cell-to-Cell Communication: Mechanisms of Morphogenesis

5. Stem Cells: Their Potential and Their Niches

PART II. GAMETOGENESIS AND FERTILIZATION: THE CIRCLE OF SEX

6. Sex Determination and Gametogenesis

7. Fertilization: Beginning a New Organism

PART III. EARLY DEVELOPMENT: CLEAVAGE, GASTRULATION, AND AXIS FORMATION

8. Rapid Specification in Snails and Nematodes

9. The Genetics of Axis Specification in Drosophila

10. Sea Urchins and Tunicates: Deuterostome Invertebrates

11. Amphibians and Fish

12.  Birds and Mammals

PART IV. BUILDING WITH ECTODERM: THE VERTEBRATE NERVOUS SYSTEM AND EPIDERMIS

13. Neural Tube Formation and Patterning

14.Brain Growth

15. Neural Crest Cells and Axonal Specificity

16. Ectodermal Placodes and the Epidermis

PART V. BUILDING WITH MESODERM AND ENDODERM: ORGANOGENESIS

17. Paraxial Mesoderm: The Somites and Their Derivatives

18. Intermediate and Lateral Plate Mesoderm: Heart, Blood, and Kidneys

19. Development of the Tetrapod Limb

20. The Endoderm: Tubes and Organs for Digestion and Respiration

PART VI: POSTEMBRYONIC DEVELOPMENT

21. Metamorphosis: The Hormonal Reactivation of Development

22. Regeneration

VII: DEVELOPMENT IN WIDER CONTEXTS

23. Development in Health and Disease: Birth, Defects, Endocrine Disruptors, and Cancer

24. Development and the Environment:  Biotic, Abiotic, and Symbiotic Regulation of Development

25. Development and Evolution: Developmental Mechanisms of Evolutionary Changes

Glossary

Author Index

Subject Index

Michael J. F. Barresi is Professor of Biological Sciences at Smith College, where he has pioneered the use of a variety of technologies to engage student in novel ways with the concepts of developmental biology as well as the researchers making the discoveries of this field.

Scott F. Gilbert is the Howard A. Schneiderman Professor of Biology Emeritus at Swarthmore College and a Finland Distinguished Professor at the University of Helsinki. He has received the Viktor Hamburger Prize in teaching from the Society of Developmental Biology as well as the Alexander Kowalevsky Award in Evolutionary Developmental Biology.