Receptor and Ion Channel Trafficking

Cell Biology of Ligand-Gated and Voltage-Sensitive Ion Channels

Stephen J. Moss, Jeremy Henley

Receptor and Ion Channel Trafficking

Cell Biology of Ligand-Gated and Voltage-Sensitive Ion Channels

Stephen J. Moss, Jeremy Henley

ISBN:

9780192632241

Binding:

Hardback

Published:

1 Sep 2002

Availability:

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Series:

Molecular & Cellular Neurobiology Series

$560.00 AUD

$641.99 NZD

Description

This book reviews the recent advances in our understanding of the molecular and cellular mechanisms that control the assembly, transport, targeting and anchoring of the protein complexes making up the most important ion channels and receptor families, fundamental to synaptic function. Improved understanding of these processes is expected to reveal novel therapeutic targets relevant to a range of disease states. Receptor and Ion-Channel Trafficking provides an integrated overview of the significant recent advances in the field of molecular neurobiology and will be essential reading for all researchers in neuroscience, neurobiology, biochemistry, cellular and molecular biology.

Contents

Ion Channels
1: Malik-Hall, Wood & Okuse: Voltage-gated sodium channels
2: Tinker: The assembly and targeting of potassium channels
3: Dolphin: Assembly and targeting of voltage-dependent calcium channels
Acetylcholine Receptors
4: Swope: Targeting of acetylcholine receptors to the postsynaptic endplate of the nerve-muscle synapse
5: Millar: Assembly and targeting of neuronal nicotinic acetylcholine receptors
Amino Acid Receptors
6: Stricker & Huganir: AMPA/kainate receptors
7: Hering & Sheng: NMDA receptor targeting
8: Harvey, von der Nuell & Harvey: Structure, assembly and targeting of glycine receptors
9: Lüscher: GABAA and GABAC receptors: regulation of assembly, localization, clustering and turnover

Authors

Edited by Stephen J. Moss , MRC-LMCB & Department of Pharmacology, University College London, UK

Jeremy Henley , MRC Centre for Synaptic Plasticity, School of Medical Sciences, University of Bristol, UK